Raman Spectroscopy Applied to Health Sciences

Raman spectroscopy has remarkable analytical abilities to scientists who want to study biological samples. The use of Raman spectroscopy within biologic samples has been increasing in the last years because it can provide biochemical information, allows discrimination between two or more sample groups, and, contrary to what happens with other spectroscopic techniques, water has no interference in the spectra. Biological samples typically do not require extensive preparation, and biochemical and structural information extracted from spectroscopic data can be used to characterize different groups. This chapter presents the general features of Raman spectroscopy and Raman spectroscopic tools relevant to the application in health sciences. In order to emphasize the potential of Raman in this research field, examples of its application in oncology, in bacterial identification and in dementia diagnosis are given

Numerical evaluation of the behavior of tubular columns in the connections to I beams with welded reverse channel

This paper presents results of numerical study on the behaviour of tubular columns in the connections to I beams with U-profiles, effected on the basis of a parametric variation of the most significant characteristics of tubular profiles. The parameters considered are the thicknesses, the widths and the diameters of the tubular columns, the filling with concrete. The main purpose is the characterisation of the nonlinear behaviour of this type of steel joints. The results of the parametric study with numerical models allow correlate the parameters considered with the structural behaviour of the connection, defined by the resistance, the stiffness and the rotation capacity and calibrate the experimental tests. The numerical models are developed with the software LUSAS.info:eu-repo/semantics/publishedVersio

Estudo experimental e calibração numérica de ligações metálicas entre vigas I e colunas tubulares

O principal objetivo da investigação apresentada é a caracterização do comportamento não linear de ligações metálicas entre vigas de perfil I e colunas tubulares com perfis U de secção soldada invertidos. Neste artigo é apresentada uma comparação entre os resultados do modelo experimental e da modelação numérica por elementos finitos, permitindo a validação do modelo e a caracterização do comportamento das principais componentes do perfil em U da ligação, nomeadamente, as associadas ao painel da alma em flexão e aos painéis dos banzos em corte, compressão e tração. Os resultados deste estudo são apresentados em termos de resistência, rigidez e capacidade de rotação da ligação. No programa de ensaios experimentais as características do comportamento não-linear das componentes do perfil são avaliadas por meio de ensaios de flexão, monotónicos e cíclicos. Os modelos numéricos foram desenvolvidos no programa de elementos finitos LUSAS, sendo calibrados com os resultados dos ensaios experimentais

Behaviour of welded reverse channel joint components of I beam to tubular columns conections

The main purpose of the investigation presented is the characterisation of the nonlinear dynamic behaviour of steel joints between I profile beams and hollow section columns with welded reverse channel. The experimental program supporting this investigation consists on the determination of the characteristics of the nonlinear cyclic behaviour of the connection between I profile beams and circular or rectangular hollow section columns. The main goal of this research program is the identification and characterization of the connection components that control the hysteretic behaviour of the connections to be used in seismic areas. The paper presents preliminary test results

Behaviour of joint components of I beam to tubular columns connections with welded reverse channel

The main purpose of this investigation is the characterisation of the nonlinear cyclic behaviour of steel joints between I profile beams to hollow section columns with welded reverse channel. In this paper a comparison is made between experimental tests and numerical finite element model results. In the experimental program the characteristics of the nonlinear behaviour of the principal reverse channel components is assessed by means of bending tests. The numerical models are developed in the software LUSAS and calibrated with the results from the experimental tests. The main focus of these tests will be on the results concerning the main components of the reverse channel detail, i.e. web face in bending, flanges panels in shear, compression and tension, in terms of strength, stiffness and rotation capacity. The parameters which have been varied in the tests are the geometry of the loaded area and the dimensions of the flanges and web of the U shaped element

Estudo numérico do comportamento de perfis em U invertidos em ligações de colunas tubulares com vigas I

Neste artigo apresenta-se um estudo paramétrico com modelos numéricos de elementos finitos de ligações entre colunas metálicas tubulares e perfis I por meio de perfis em U invertidos soldados. Para calibração dos modelos, os resultados foram comparados com os obtidos em ensaios experimentais. Com os modelos numéricos desenvolvidos, pretende-se avaliar quais os principais parâmetros que condicionam o comportamento dos elementos da ligação, em especial o das componentes da alma e dos banzos do perfil em U. Os parâmetros escolhidos para di-ferenciação dos modelos foram as dimensões dos elementos do perfil e as dimensões da área carregada

Behaviour of welded reverse channel joint components of I beam to tubular columns conections

O principal objetivo da investigação apresentada é a caracterização do comportamento não linear de ligações metálicas entre vigas de perfil I e colunas tubulares com perfis U de secção soldada invertidos. Neste artigo é apresentada uma comparação entre os resultados do modelo experimental e da modelação numérica por elementos finitos, permitindo a validação do modelo e a caracterização do comportamento das principais componentes do perfil em U da ligação, nomeadamente, as associadas ao painel da alma em flexão e aos painéis dos banzos em corte, compressão e tração. Os resultados deste estudo são apresentados em termos de resistência, rigidez e capacidade de rotação da ligação. No programa de ensaios experimentais as características do comportamento não-linear das componentes do perfil são avaliadas por meio de ensaios de flexão, monotónicos e cíclicos. Os modelos numéricos foram desenvolvidos no programa de elementos finitos LUSAS, sendo calibrados com os resultados dos ensaios experimentais.ABSTRACT: The main purpose of this investigation is the characterisation of the nonlinear behaviour of steel joints between I profile beams to hollow section columns with welded reverse channel. In this paper a comparison is made between experimental tests and numerical finite element model results, enabling the model validation and determinate the behaviour characteristics of the main components of the reverse channel joining detail, i.e. web face in bending, flanges panels in shear, compression and tension. This study results are presented in terms of resistance, stiffness and rotation capacity of the joint. In the experimental program the characteristics of the nonlinear behaviour of the principal reverse channel components are assessed by means of bending tests, monotonic and cyclic. The numerical models are developed with the software LUSAS and calibrated with the results from the experimental tests

Avaliação numérica do comportamento de colunas tubulares nas ligações a vigas I com perfis em U invertidos soldados

O artigo apresenta resultados do estudo numérico relativo ao comportamento de colunas tubulares nas ligações a vigas I com perfis em U, efetuado com base numa variação paramétrica das características mais significativas dos perfis tubulares. Os parâmetros considerados são as espessuras, as larguras e os diâmetros das colunas tubulares, e o seu enchimento com betão. Os resultados do estudo paramétrico com os modelos numéricos permitem relacionar os parâmetros considerados com o comportamento estrutural da ligação, nomeadamente a resistência, as rigidezes e a capacidade de rotação. Dos resultados obtidos, conclui-se que a variação destes parâmetros altera significativamente o comportamento global da ligação

Frailty in cardiovascular disease: Screening tools

Cardiovascular disease (CVD) is the leading cause of death in developed countries and disproportionately affects older adults. Frailty is a complex clinical syndrome with multiple causes and contributing factors in which there is increased vulnerability when exposed to a minor stressor and increased risk for adverse outcomes, such as disability, hospitalization and mortality. Frailty is an important prognostic factor in patients with CVD, and so identifying this feature when assessing these patients may help to individually tailor cardiovascular treatment. The first step is to identify frailty. Several tools have been validated as screening methods for frailty. However, they diverge with regard to complexity, nature, feasibility and the outcome they can predict. The aim of this review is to describe the available screening tools for frailty and to examine their usefulness in patients with CVD.info:eu-repo/semantics/publishedVersio

Courses and researches in the nutrition area on the pages of the bulletin institutional magazine of SAPS:(Food Service Social Security);(1944-1946)

Objective: To analyze the process of appearance of the technical courses and professionals Nutritionists and antecedents, created by the Food Service of Social Security - SAPS, through the Collection of its Bulletins. Method: The bibliographical research of the Bulletins was carried out, Institutional Magazine that circulated in the period from November 1944 to November 1946, with the target audience being the employees of the SAPS Restaurants. Results: The analysis of these sources suggests that this Bulletin registered the evolution of these courses as well as several researches developed in the area of ​​nutrition, with abundant written and imagistic documentation, through facsimiles subtitled within these publications. Conclusion: The Bulletins brought journalistic coverage of great importance and significance to the history of the profession, composed of 118 articles and 173 facsimiles with rich details. It is pointed out to the relevance of these documents not only for the history of the profession of Nutritionist as of its antecedents